ABSTRACT

This technical briefing provides information about high efficiency air filters utilised within cleanrooms for pharmaceutical and healthcare applications.

Information includes details relating to the type of filtration media typically utilised, the filtration removal mechanisms and the approach to filter testing and classification…

KEYWORDS: Aerosol Particles, Air Velocity, Airborne Particles, Aseptic Conditions, Aseptic Processing, Boron, Classification, Clean Zones, Cleanrooms, Contaminated Air, Contamination, Diffusion (Brownian Motion), Efficient Particulate Air Filter (EPA), EN 1822-1: 2019, Energy Costs, Expanded PTFE (ePTFE). Filter Testing, Filtration Media, Glove Boxes, Group E (EPA) Filters, Healthcare, High Efficiency Air Filters, High Efficiency Particulate Air Filter (HEPA), Inertial Impaction, In-situ Filter Leak Testing, Interception, ISO 29463-1: 2017, Isolators, Light Scattering Airborne Particle Counter (LSAPC), Microbe-carrying Particles (MCPs), Most Penetrating Particle Size (MPPS), Penetration (Leakage), Pharmaceutical, Photometer, RABS, Screening (Sieving), Separative Devices, Space Saving, Ultra Low Penetration Air Filter (ULPA), Van der Waals Forces.

More detailed information and explanation regarding high efficiency air filters, including in-situ leak testing failures, are included in the following Honeyman training courses;

1. Cleanrooms: Principles in Practice®
2. Microbial Risk Management During Cleanroom Operations
3. Aseptic Processing: Principles in Practice®

Further related information can be found in the following associated briefs:

1. Airborne Particle Counting Using LSAPC – Technical Briefing (PDF)
2. Cleanroom Classification – Technical Briefing (PDF)
3. Cleanroom Testing – Technical Briefing (PDF)
4. High Efficiency Air Filters – Technical Briefing (PDF)
5. Cleanroom Airflow Visualisation – Technical Briefing (PDF)
6. Liquid and Gas Filtration – Technical Briefing (PDF)
7. Cleanroom Garment – Technical Briefing (PDF)